On December 14, 2017 at 08:38 UTC the Russian “Soyuz MS-05” landing capsule landed safely in Kazakhstan. The spacecraft delivered to Earth the 3 members of ISS’s Expedition 53 – Russian cosmonaut Sergey Ryazansky, American astronaut Randolph Bresnik and Italian astronaut Paolo Nespoli. They spent in space 139 days. Three other ISS crew members – Russian cosmonaut Aleksandr Misurkin; American astronauts Mark Vande Hei and Joseph Acaba remained in orbit aboard the International Space Station as the Expedition 54 crew. The undocking of Soyuz MS-05 marked the end of Expedition 53 and the start of Expedition 54.

On December 14, 2017 at 05:15 UTC the Russian “Soyuz MS-05” spacecraft undocked from the International Space Station to deliver to Earth the 3 members of Expedition 53 – Russian cosmonaut Sergey Ryazansky, American astronaut Randolph Bresnik and Italian astronaut Paolo Nespoli.

On December 6, 2017, the US "Cygnus” (CRS OA-8 ““Eugene Cernan”) unmanned supply spacecraft was undocked from the International Space Station. The spacecraft, which had been attached to the space station since November 14, 2017, was released by US astronaut Mark Vande Hei aboard the station using the orbiting complex's huge robotic arm at 13:11 UTC. It was the 8^th successful flight of "Cygnus” to the ISS. But Cygnus CRS-8 spacecraft’s mission is not over.

In the period from November 20 till November 21, 2017 several micro satellites were launched from the International Space Station. On November 20, 2017 at 08:05 UTC - EcAMSat (E.coli AntiMicrobial Satellite). On November 20, 2017 at 12:25 UTC - ASTERIA (Arcsecond Space Telescope Enabling Research in Astrophysics). On November 20, 2017 at 17:02 UTC - Dellingr (RBLE, Radiation Belt Loss Experiment). On November 21, 2017 at 08:25 UTC - TechEdSat-6 (Technical and Education Satellite-6, TES-6). On November 21, 2017 at 11:40 UTC - OSIRIS-3U (Orbital Satellite for Investigating the Response of the Ionosphere to Stimulation and Space Weather). ASTERIA, Dellingr and OSIRIS-3U were delivered to the ISS by the “Dragon SpX-12” spacecraft. EcAMSat and TechEdSat-6 were delivered to the ISS by the “Cygnus OA-8” spacecraft.

On November 14, 2017, the American "Cygnus” (CRS OA-8 “Eugene Cernan”) private unmanned supply spacecraft was docked to the International Space Station (ISS). The Cygnus spacecraft was grappled by a robotic arm operated by astronauts inside the space station at 10:04 UTC. The cargo spacecraft was docked to the station’s "Unity” module at 12:15 UTC. The spacecraft delivered about 3300 kilograms of supplies to the Space Station. It was the 8^th docking of a "Cygnus” spacecraft with the ISS.

On November 12, 2017 at 12:19 UTC the "Cygnus” privately owned U.S. unmanned supply spacecraft was launched from the Mid-Atlantic Regional Spaceport (MARS), a commercial space launch facility located at the southern tip of NASA's Wallops Flight Facility on Wallops Island, Virginia, USA. The spacecraft was orbited by the “Antares 230” rocket-carrier. The "Cygnus” (CRS OA-8 “Eugene Cernan”) unmanned supply spacecraft, built by U.S. space firm Orbital Sciences Corp., was orbited on its cargo resupply mission to the International Space Station. CRS means Commercial Resupply Services. The "Cygnus” (CRS OA-8) is the 8th successful flight of the Orbital ATK uncrewed resupply spacecraft Cygnus.

On November 6, 2017 American astronaut Richard Francis Gordon passed away. He was 88. Gordon performed two space flight, serving as pilot on the Gemini 11 mission in 1966 and command module pilot on Apollo 12 in 1969, logging more than 13 days in space.

On October 24, 2017 at 09:45 UTC, the “Kestrel Eye-2M” was launched from the International Space Station. “Kestrel Eye”, also referred to as “Kestrel Eye-2M”, is a small imaging technology demonstration spacecraft project of the U.S. Army Space and Missile Defense Command/U.S. Army Forces Strategic Command (SMDC/ARSTRAT) Technical Center (TC) in Huntsville, AL. The satellite was delivered to the ISS by the US “Dragon” CRS-12 unmanned supply spacecraft in August 2017.

On October 23, 2017 American astronaut Paul Joseph Weitz passed away. Weitz has passed away from cancer. He was 85.

On October 20, 2017, American astronauts Randolph Bresnik and Joseph Acaba performed a spacewalk. The astronauts installed a new high definition camera, replaced a degraded camera on a recently attached robot arm grapple fixture, finished lubricating the mechanism and carried out a variety of other tasks. The EVA (extravehicular activity) lasted 6 hours and 49 minutes. This was the fifth spacewalk for Randolph Bresnik and the third for Joseph Acaba.